Central Core Disease
Starts in infancy or early childhood with poor muscle tone, infants with central core disease have delays in reaching motor milestones.Other symptoms may include skeletal deformities, including joint dislocations and scoliosis (spinal curvature), often occur; susceptibility to malignant hyperthermia, a dangerous adverse reaction to anesthesia. Can be inherited from one, or usually by means of a recessive gene, both, parents. Progression varies: may be disabling.
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