Phosphofructokinase Deficiency
Phosphofructokinase Deficiency, also known as Tarui's Disease, strikes people in their teen years to their thirties. The major symptom is muscle fatigue that exercise turns into severe cramps. Someone with this may also experience nausea, vomiting, muscle damage and rust-colored urine (myoglobinuria). Though disease progression is variable, food high in carbohydrates makes symptoms worse. This disease is autosomal recessive, inherited by means of a defective gene from each parent.
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