Spinal Muscular Atrophy Type 3
Also known as SMA3 or Kugelberg-Welander Disease, onset is after 18 months, but many symptoms are the same as Spinal Muscular Atrophy Type 2, with severe weakness in muscles closest to the center of the body, such as those of the shoulders, hips, thighs and upper back. Respiratory muscle weakness and spinal curvature can develop. Disease progresses slowly, with walking ability usually maintained until at least adolescence. Wheelchair often required later in life. Inherited by means of a faulty recessive gene from both parents.
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